Preservatives for Cosmetic Formulations

AMTicide Coconut | Lactobacillus (and) Cocos Nucifera (Coconut) Fruit Extract

  • Usage Rate: 2.0%-4.0%
  • pH Range: 3-8
  • Max Temperature: 70°C (158°F)
  • Solubility: Soluble in water, glycerin and propylene glycol, immiscible with oils
  • Effective against: Yeast and Mold
  • Activity: Fungicidal
  • Stated free from: N/A
  • Contradictions: N/A
  • Country Restrictions: N/A
  • Other Notes: Often used in conjunction with other broad-spectrum preservatives to strengthen activity against yeast and mold. Commonly paired with Leucidal Liquid.
  • More Info: https://chemistryconnection.com/sds/data/pdf/AMTicide_Coconut-Technical_Data_Sheet-v4.pdf

Barguard CP: See Jeecide Cap 2 | Caprylyl Glycol (and) Phenoxyethanol (and) Hexylene Glycol

Caprylyl Glycol | Caprylyl Glycol

  • Usage Rate: 1-2%
  • pH Range: “broad”
  • Max Temperature: 60°C (140°F)
  • Solubility: Soluble in oil, glycol and alcohol
  • Effective against: Bacteria
  • Activity: Biostatic, Humectant
  • Stated free from:
  • Contradictions:
  • Country Restrictions: N/A
  • Other Notes: Also known as 1,2 Octanediol, Caprylyl Glycol enhances and boosts the activity of other preservatives. It often acts as an emollient, humectant, wetting agent, or viscosity booster in addition to being part of a preservative system
  • More Info: https://www.ulprospector.com/en/eu/PersonalCare/Detail/352/10336/Lexgard-O–Caprylyl-Glycol

Diazolidinyl Urea | Diazolidinyl Urea

  • Usage Rate: 0.5%
  • pH Range: 3 – 9
  • Max Temperature: 60°C (140°F)
  • Solubility: Water soluble
  • Effective against: Effective against Bacteria, weak activity against yeast and mold
  • Activity: Biocidal
  • Stated free from: paraben free
  • Contradictions:
  • Country Restrictions: Not permitted in Japan
  • Other Notes: Also known as Diazolidinyl Urea, N,N’-Bis(Hydroxymethyl)Urea
  • More Info: https://www.cosmeticsinfo.org/ingredient/diazolidinyl-urea/

Euxyl PE 9010 | Phenoxyethanol (and) Ethylhexylglycerin

  • Usage Rate: 0.5%-1.1%
  • pH Range: 0-12
  • Max Temperature: 120°C (248ºF)
  • Solubility: Highly soluble in polar solvents, slightly water soluble
  • Effective against: Broad spectrum: gram negative and gram positive bacteria, yeast, mold
  • Activity: Biostatic with biocidal properties
  • Stated free from: Paraben free and formaldehyde free.
  • Contradictions: Ethoxylated surfactants
  • Country Restrictions: N/A
  • Other Notes: N/A
  • More Info: https://www.rossorg.com/wp-content/uploads/2019/11/Euxyl-PE-9010-Brochure.pdf

Geogard ECT: see preservative ECO |Benzyl Alcohol & Salicylic Acid & Glycerin & Sorbic Acid

Geogard Ultra | Gluconolactone (and) Sodium Benzoate

  • Usage Rate: 0.75% – 1.5%, no more than 2%
  • pH Range: 3-6
  • Max Temperature: Can be added at both room and elevated temperatures
  • Solubility: Soluble in water, glycerin, and propylene glycol, and mineral oil
  • Effective against: Broad spectrum; gram negative and gram positive bacteria, yeast, mold
  • Activity: Bacteriostatic, Fungistatic, Chelator
  • Stated free from: paraben free and formaldehyde free
  • Contradictions: N/A
  • Country Restrictions: Sodium Benzoate (and benzoic acid) is the restricting ingredient in Geogard Ultra. It generally comprises 22% of the preservative blend. EU regulations stipulate max concentrations of 2.5% SB for rinse off products, and 0.5% SB for leave on products. Japan regulations stipulate max concentrations of 1.0% SB, US regulations stipulate max concentrations of 5.0% SB
  • Other Notes: Can cause pH to drift down and might need to be accompanied with Sodium Citrate to stabilize pH. Check the linked document to see manufacturer suggestions. ECOCERT/COSMOS-accepted
  • More Info: https://glenncorp.com/wp-content/uploads/2018/02/2017_10_Geogard-Ultra_TDS_d11_LowRes.pdf

Germaben II | Propylene Glycol (and) Diazolidinyl Urea (and) Methylparaben (and) Propylparaben

Gluconolactone | Glucono Delta Lactone/Gluconolactone

Jeecide Cap 2 | Caprylyl Glycol (and) Phenoxyethanol (and) Hexylene Glycol

  • Usage Rate: 0.7% – 1%
  • pH Range: 4-8
  • Max Temperature: <80ºC (176ºF)
  • Solubility: Oil Soluble, Water dispersible
  • Effective against: Broad spectrum; gram negative and gram positive bacteria, yeast, mold
  • Activity:
  • Stated free from: paraben free, formaldehyde free, formaldehyde donor free
  • Contradictions: N/A
  • Country Restrictions: N/A
  • Other Notes: Also known as Lexgard HPO, Barguard CP, Jeecide CAP 2, TKB’s Cap 2
  • More Info: https://biotechnologia.pl/uploads/product/leaflet/850933/Preservatives_Brochure.pdf

Leucidal® Liquid | Leuconostoc/Radish Root Ferment Filtrate

Lexgard HPO: See Jeecide Cap 2 | Caprylyl Glycol (and) Phenoxyethanol (and) Hexylene Glycol

Lexgard O: see Caprylyl Glycol | Caprylyl Glycol

Liquid Germall Plus | Propylene Glycol (and) Diazolidinyl Urea (and) Iodopropynyl Butylcarbamate

  • Usage Rate: 0.1%-0.5%
  • pH Range: 3-8
  • Max Temperature: <50ºC (122ºF)
  • Solubility: Water miscible, propylene glycol miscible, glycerine miscible
  • Effective against: Broad spectrum: gram negative and gram positive bacteria, yeast, mold
  • Activity: Biocidal
  • Stated free from: Paraben free, does contain formaldehyde releasers
  • Contradictions: None known
  • Country Restrictions: EU, Japan: restrictions exist due to the ingredient Iodopropynyl Butylcarbamate
  • Other Notes: Regulatory Profile of Iodopropynyl ButylcarbamateEU: Maximum of 0.02% in rinse off products, maximum of 0.01% in leave on products, maximum of 0.0075% in deodorants/antiperspirants. Not for use in oral hygiene products. Not for use in products for children <3 years except bath products, shower gels, and shampoos JAPAN: Approved for use in all cosmetics; not to be used in aerosols NOTE: MAXIMUM RECOMMENDED USE LEVEL OF 0.05% LIQUID GERMALL PLUS IN A FINISHED FORMULATION RESULTS IN 0.002% IPBC CONCENTRATION–Well within limits!
  • More Info: https://cdn.shopify.com/s/files/1/0026/8317/5001/files/tech_data_liquid_germall_plus.pdf?42300725444058841

NeoDefend | Gluconolactone (and) Sodium Benzoate

  • Usage Rate: 0.75% – 1.5%, up to 2%
  • pH Range: 3-6
  • Max Temperature:
  • Solubility: Soluble in water, propylene glycol, glycerin and mineral oil
  • Effective against:
  • Activity: Bacteriostatic, Fungistatic
  • Stated free from: N/A
  • Contradictions: The use of NeoDefend and L-Ascorbic Acid and Citric Acid in the same cosmetic formulations should be avoided
  • Country Restrictions: N/A
  • Other Notes: Can cause pH of formulations to drift down which may require adjusting. NeoDefend’s ingredients are accepted by ECOCERT as preservatives in certified organic cosmetics
  • More Info: N/A

Optiphen | Phenoxyethanol (and) Caprylyl Glycol

  • Usage Rate: 0.75%-1.5%
  • pH Range: 0-12
  • Max Temperature: <80ºC (176ºF)
  • Solubility: Oil soluble, limited water solubility
  • Effective against: Broad spectrum: highly effective against bacteria, less effective against yeast and mold
  • Activity: Biocidal
  • Stated free from: Paraben free, Formaldehyde free, Formaldehyde donor free
  • Contradictions: N/A
  • Country Restrictions: N/A
  • Other Notes: N/A
  • More Info: https://cdn.shopify.com/s/files/1/0026/8317/5001/files/TIB_VC-850_Optiphen.pdf?v=1686081230

Optiphen Plus | Phenoxyethanol (and) Caprylyl Glycol (and) Sorbic Acid

  • Usage Rate: 0.75%-1.5%
  • pH Range: Below 6
  • Max Temperature: <80ºC (176ºF)
  • Solubility: Oil soluble, limited water solubility
  • Effective against: Broad spectrum: effective against bacteria, yeast and mold
  • Activity: *
  • Stated free from: Paraben and formaldehyde-free
  • Contradictions: N/A
  • Country Restrictions: N/A
  • Other Notes: Might require vigorous stirring (or shear blending) in aqueous solutions
  • More Info: https://azeliscanada.com/wp-content/uploads/2020/01/Optiphen-Plus-Brochure.pdf

Phenonip | Phenoxyethanol (and) Methylparaben (and) Ethylparaben (and) Butylparaben (and) Propylparaben (and) Isobutylparaben

  • Usage Rate: 0.25%-1%
  • pH Range: 3-8
  • Max Temperature: <80°C (176°F)
  • Solubility: Oil soluble, can be dispersed in water under some circumstances (see More Info)
  • Effective against: Broad spectrum: gram negative and gram positive bacteria, yeast, mold
  • Activity: Biocidal
  • Stated free from: Formaldehyde Free, Formaldehyde donor free
  • Contradictions: N/A
  • Country Restrictions: N/A
  • Other Notes: N/A
  • More Info: https://cdn.shopify.com/s/files/1/0026/8317/5001/files/tech_data_phenonip.pdf?14406176490749443445

Phenoxyethanol | Phenoxyethanol

  • Usage Rate: 0.25 – 1%
  • pH Range: 3-12
  • Max Temperature: 85°C (185°F)
  • Solubility: Highly oil soluble, limited water solubility, miscible with propylene glycol and glycerin
  • Effective against: Effective against bacteria, weak against yeast and mold
  • Activity: Biocidal
  • Stated free from: Paraben free, Formaldehyde donor free
  • Contradictions: Inactivated by highly ethoxylated compounds
  • Country Restrictions: UK and EU
  • Other Notes: In surfactant solution systems, the water must be saturated with Phenoxyethanol for activity
  • More Info: https://health.ec.europa.eu/system/files/2021-08/sccs_o_195_0.pdf

Plantaserve E: See Euxyl PE 9010 |Phenoxyethanol (and) Ethylhexylglycerin

Plantaserve P: See Saliguard PCG | Phenoxyethanol (and) Caprylyl Glycol (and) Propylene Glycol

Potassium Sorbate | Potassium Sorbate

  • Usage Rate: 0.1 – 0.6%
  • pH Range: 2-6.5
  • Max Temperature: <80ºC (176ºF)
  • Solubility: Water soluble
  • Effective against: Strongly antifungal, some protection against yeast, weak against bacteria
  • Activity: Fungicidal
  • Stated free from: paraben and formaldehyde-free
  • Contradictions: Sorbic acid is an unsaturated fatty acid, and as such, is subject to oxidation
  • Country Restrictions: N/A
  • Other Notes: COSMOS & ECOCERT certified
  • More Info: https://ecommons.cornell.edu/server/api/core/bitstreams/3d33a25d-0136-45c6-8bcb-ebe64d5b80a3/content

Preservative ECO | Benzyl Alcohol & Salicylic Acid & Glycerin & Sorbic Acid

Saliguard: PCG | Phenoxyethanol (and) Caprylyl Glycol (and) Propylene Glycol

  • Usage Rate: 0.5%-1.0%
  • pH Range: 3-10
  • Max Temperature: <60°C (140°F)
  • Solubility: Water soluble, Oil dispersible? (indicated for both aqueous and anhydrous formulas without any other specifications… so?)
  • Effective against: Broad spectrum: gram negative and gram positive bacteria, yeast, mold
  • Activity:
  • Stated free from: paraben free, formaldehyde donor free
  • Contradictions: N/A
  • Country Restrictions: N/A
  • Other Notes: N/A
  • More Info: https://www.knowde.com/stores/salicylates-and-chemicals-private-limited/products/saliguard-pcg

Saliguard: EHGP | Ethylhexylglycerin, Phenoxyethanol

  • Usage Rate: 0.5-1.50%
  • pH Range: 2-12
  • Max Temperature: 120°C (248ºF)
  • Solubility: Water soluble, Oil dispersible? (indicated for both aqueous and anhydrous formulas without any other specifications… so?)
  • Effective against:
  • Activity: Broad spectrum: gram negative and gram positive bacteria, yeast, mold
  • Stated free from: paraben free and formaldehyde free.
  • Contradictions: N/A
  • Country Restrictions: N/A
  • Other Notes: N/A
  • More Info: https://www.knowde.com/stores/salicylates-and-chemicals-private-limited/documents/91433

Sharomix™ AM24 | Methylpropanediol, Caprylyl Glycol, Polyquaternium-80, Didecyldimonium Chloride

  • Usage Rate: 0.5-1.0%
  • pH Range: not pH dependent per manufacturer
  • Max Temperature: not indicated, however it’s likely the range of Caprylyl Glycol (60°C (140°F) as it seems to be the limiting ingredient
  • Solubility: Water Soluble
  • Effective against: Effective against bacteria, fungus, yeast, mold
  • Activity:
  • Stated free from: N/A
  • Contradictions: N/A
  • Country Restrictions: N/A
  • Other Notes: https://www.coastsouthwest.com/introducing-sharon-labs-new-preservatives/
  • Other Notes: https://drugs.ncats.io/drug/1VU15B70BP
  • More Info: Harnesses the preservative-boosting activity of diols and glycols, with a sulfopolyester quaternary ammonia salt. I could not find much information on this preservative and would be interested in seeing testing and technical data sheets to verify the claims that it isn’t pH dependent. This is a very intriguing option!

Sodium Benzoate | Sodium Benzoate

  • Usage Rate: up to 1%
  • pH Range: 3-6
  • Max Temperature: <60°C (140°F)
  • Solubility: Water soluble
  • Effective against: Effective against fungus, some protection against yeast
  • Activity: Bacteriostatic, Fungistatic
  • Stated free from: N/A
  • Contradictions: Inactivated by non-ionics and high pH
  • Country Restrictions: EU regulations stipulate max concentrations of 2.5% Sodium benzoate for rinse off products, and 0.5% Sodium benzoate for leave on products. Japan regulations stipulate max concentrations of 1.0% sodium benzoate, US regulations stipulate max concentrations of 5.0% Sodium benzoate
  • Other Notes: pH may need to be adjusted down to maintain activity. Sodium Benzoate should always be used in conjunction with other preservatives to form a complete system
  • More Info: N/A

Sorbic Acid | Sorbic Acid (2,4-hexadienoic acid)

  • Usage Rate: 0.1% – 0.5%
  • pH Range: 5 or lower
  • Max Temperature: <60°C (140°F)
  • Solubility: Soluble in alcohol, glycerin, propanediol, some oils, and glycerin. Very slightly soluble in water
  • Effective against: Effective against mold, fair against yeast, poor against most bacteria
  • Activity: Fungicidal, Fungistatic,
  • Stated free from: N/A
  • Contradictions: N/A
  • Country Restrictions: N/A
  • Other Notes: Potassium sorbate is highly soluble in water and is often a better choice for cosmetics
  • More Info: https://www.ingredientstodiefor.com/files/PotassiumSorbate.pdf

TriStat Eco | Benzyl Alcohol, Glyceryl Caprylate and Glyceryl Undecylenate

  • Usage Rate: 1.0-2.0%
  • pH Range: 4-8
  • Max Temperature: <80°C (176°F) no longer than 30 minutes
  • Solubility: Soluble in alcohol, glycerin, glycols and polar oils, very slightly soluble in water
  • Effective against: Active against bacteria, yeasts & molds.
  • Activity: Biocidal
  • Stated free from: N/A
  • Contradictions: N/A
  • Country Restrictions: N/A
  • Other Notes: COSMOS & ECOCERT certified
  • More Info: *TRI-K

TriStat D2 | Propylene glycol, Diazolidinyl Urea, Methylparaben, Propylparaben

  • Usage Rate: 0.03%-0.70%
  • pH Range: 3-7.5
  • Max Temperature: <60°C (140°F)
  • Solubility: Water Soluble
  • Effective against: Effective against bacteria, weak against yeast and mold
  • Activity: Biocidal, Fungicidal
  • Stated free from: N/A
  • Contradictions: N/A
  • Country Restrictions: Not permitted in Japan
  • Other Notes:
  • More Info: https://www.ulprospector.com/en/na/PersonalCare/Detail/611/77490/TRIstat-D2

TriStat PCG90 | Caprylyl Glycol, Phenoxyethanol

  • Usage Rate: 0.5%-1.5%
  • pH Range: 4-8
  • Max Temperature: <60°C (140°F)
  • Solubility: Water Soluble
  • Effective against: Broad spectrum: highly effective against bacteria, and yeast. less effective against mold until the 7-day mark at which point it is equally effective (use hurdle technology)
  • Activity: Biocidal
  • Stated free from: paraben free, Formaldehyde donor free
  • Contradictions: N/A
  • Country Restrictions: N/A
  • Other Notes: ECOCERT/COSMOS accepted
  • More Info: https://www.knowde.com/stores/tri-k-industries-inc/products/tristat-pcg90